3.1. Reputation-based protection settings
3.1.1. Check apps and files
Disable Check apps and files
GPO
Computer Configuration › Administrative Templates › Windows Components › File Explorer › Configure Windows Defender SmartScreen
☑
DISABLED
Updated: 2021-02-19 Reference
3.1.2. SmartScreen for Microsoft Edge
Edge will eventually be removed; until then, leave enabled for Edge browser.
3.1.3. Potentially unwanted app blocking
Disable Potentially unwanted app blocking
Blocking downloads cannot be managed. Leave download blocking enabled.